
GHK CU 50mg
Original price was: $84.50.$65.00Current price is: $65.00.
Popular Uses:
✔ Anti-aging skin support (fine lines, firmness, elasticity)
✔ Hair growth and scalp health
✔ Post-procedure skin healing
✔ May support muscle and nerve regeneration
WHAT IS GHK-CU?
GHK-CU (Glycyl-L-Histidyl-L-Lysine-Copper) is a naturally occurring copper-binding tripeptide found endogenously in human plasma, saliva, and urine. MW: 340.38 Da as the free peptide; 403.93 Da as the Cu(II) complex. First isolated from human plasma albumin by Loren Pickart (1973). The copper(II) ion coordinates with the glycine amino terminus, histidine imidazole nitrogen, and lysine amine in a square planar coordination geometry. This compound is supplied in synthetic research-grade form chemically identical in sequence to the endogenous peptide, produced via SPPS.
Note: At 50mg per vial, this product offers higher compound concentration than standard research-grade GHK-CU 50mg offerings, IGF-1 LR3 1mg, enabling higher-volume experimental protocols or multiple reconstituted aliquots per vial.
MECHANISM OF ACTION IN PRECLINICAL MODELS
• ECM Remodelling — MMP Regulation: GHK-CU 50mg has been studied in dermal fibroblast cultures for modulation of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs), regulators of extracellular matrix turnover in wound healing model systems.
• Collagen Synthesis Pathway: Type I and Type III collagen production modulation via TGF-β signalling in dermal fibroblast cell culture models.
• Angiogenesis: VEGF-mediated angiogenic signalling pathway activation observed in wound model tissue systems.
• Gene Expression: A 2012 genomics analysis (PMID: 22214857) identified GHK-CU 50mg influence on expression of 31% of genes associated with tissue remodelling pathways in skin fibroblast models.
⚠️ Research Use Only: For in-vitro laboratory research by qualified investigators only. Not for human or animal use.
COA / HPLC / MS

Storage Instructions:
Our products are manufactured using lyophilization (freeze-drying), ensuring stability for shipping and storage at room temperature for 3–4 months. Lyophilization involves freezing the peptides and applying low pressure to sublimate water from solid to gas, resulting in a stable, crystalline white powder (lyophilized peptide).
- Before Reconstitution: Store lyophilized peptides in a cool, dark place. For short-term storage (days to weeks), refrigeration at 4°C (39°F) is sufficient. For long-term storage (months to years), freezing at -80°C (-112°F) is recommended to maintain stability.
- After Reconstitution: Once mixed with bacteriostatic water, peptides must be refrigerated at 4°C (39°F) and used within 30 days to ensure stability. Keep them protected from light.
Structure

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